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Metabolic Psychiatry is having a growing impact on serious mental illness treatment.  With more clinicians engaged, studies underway, and lives transformed, the momentum continues to build.

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General Questions

What is the connection between metabolic health and mental health?

Numerous studies indicate that those with poor metabolic health, including impairments like insulin resistance, metabolic syndrome, pre-diabetes, or type 2 diabetes, have a significantly increased risk of serious mental illness such as bipolar disorder, major depression, or schizophrenia.

The correlation holds in the opposite direction as well; those with serious mental illness have a higher likelihood of having metabolic dysfunction. Clinical experience and emerging evidence suggest that improving metabolism through ketogenic diets, as well as smart approaches to nutrient deficiencies, sleep, exercise, and stress reduction, can create mental health. This is the connection we explore at Metabolic Mind.

THINK+SMART, our free metabolic mental health program, including e-books, worksheets, and a guided email course, helps individuals personalize their wellness journeys using these strategies.

What are metabolic therapies for mental health?

Metabolic therapies for mental health are interventions or treatments that improve systemic metabolic and mitochondrial function to prevent, reduce, or eliminate symptoms of psychiatric illness. Typical therapies include nutritional ketosis, sleep management, movement/exercise, substance use management, meditation, and mindfulness. In addition, medications that improve insulin resistance are sometimes used to address psychiatric symptoms.

What mental illnesses can be helped by metabolic therapies?

Metabolic therapies are being explored for a wide range of mental health conditions, particularly serious mental illnesses. At Metabolic Mind, the primary focus is on conditions such as major depressive disorder, bipolar disorder, schizophrenia, schizoaffective disorder, and anorexia nervosa.

Research and clinical perspectives, including those outlined by Dr. Chris Palmer in his book Brain Energy, suggest that if mental illness is linked to metabolic and mitochondrial dysfunction in the brain, then many psychiatric conditions may potentially benefit from metabolic approaches.

According to Dr. Palmer, the scientific literature has identified mitochondrial dysfunction in the following psychiatric conditions:

  • schizophrenia
  • schizoaffective disorder
  • bipolar disorder
  • major depression
  • autism
  • anxiety disorders
  • obsessive-compulsive disorder (OCD)
  • post-traumatic stress disorder (PTSD)
  • attention deficit/hyperactivity disorder (ADHD)
  • anorexia nervosa
  • alcohol use disorder (alcoholism)
  • marijuana use disorder
  • opioid use disorder
  • borderline personality disorder
  • Alzheimer’s disease

Additionally, the field of metabolic neurology is expanding, with clinicians such as Dr. Matthew Phillips and researchers such as Steven Cunnane exploring metabolic therapies for neurodegenerative disorders, including dementia, Parkinson’s disease, ALS, and Huntington’s disease. In our expert by experience stories featured in THINK+SMART, you will find individuals across a wide range of psychiatric and neurological conditions who report meaningful improvements with metabolic therapies.

What is ketogenic therapy for mental illness?

Ketogenic therapy for mental illness is a sustained dietary strategy that improves metabolic function by inducing therapeutic nutritional ketosis to prevent, reduce, or eliminate symptoms of psychiatric illness.

There can be many different components of ketogenic therapy, but it often includes selecting a low-carb dietary strategy (what and what not to eat), establishing a target macronutrient ratio (typically 60% calories or more from fat), measuring ketones daily, and restricting timing of eating (when and when not to eat). Ketogenic therapy can also include tracking metabolic and mental health measures (see our sample lab order here), and supplementing with electrolytes, MCT oil, exogenous ketones, carnitine, Vitamin D, B12, and other nutrients.