Dr. Cynthia Calkin and colleagues demonstrate that improving insulin sensitivity in treatment-resistant bipolar depression led to remission after decades of illness.
New Results: First RCT for Schizophrenia & Bipolar Disorder. Learn more.
Treating Insulin Resistance With Metformin as a Strategy to Improve Clinical Outcomes in Treatment-Resistant Bipolar Depression
Dr. Cynthia Calkin and colleagues demonstrate that improving insulin sensitivity in treatment-resistant bipolar depression led to remission after decades of illness.
A randomized controlled trial demonstrated metabolic, psychiatric, and cognitive improvements following a ketogenic diet in people with psychotic disorders.
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In a virtual 14-week pilot, participants maintained nutritional ketosis with high retention and tolerability, alongside significant reductions in depression, anxiety, and anhedonia.
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In a 6-week randomized trial, adults with treatment-resistant depression had modest depressive symptom improvements on the ketogenic diet.
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