The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review

First Ketogenic Therapy for Anorexia Nervosa Trial. Learn more.

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Reviews

The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review

Drs. Shebani Sethi and Judy Ford call for more clinical trials to address the potential beneficial effects of the ketogenic diet in people with serious mental illness.

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Reviews

Metabolic Plasticity: An Evolutionary Perspective on Metabolic and Circadian Dysregulation in Bipolar Disorder

This perspective review examines bipolar disorder through a metabolic lens. It highlights how nutrition, seasonal light, and metabolic shifts may contribute to symptom instability.

Reviews

Clinical Insights Into the Mechanistic Crossroads of Lamotrigine and Therapeutic Ketosis in Bipolar DepressionMedically Supervised Ketogenic Diet as an Adjunctive Treatment for Moderate to Severe Depression: A Pilot Study

Lamotrigine treats both epilepsy and bipolar disorder via shared neurobiology. This review explores whether therapeutic ketosis may synergistically enhance mood stabilization and metabolic health.

Reviews

The Ketogenic Diet for Depression and Anxiety: Implications for Practice

This review suggests low-carbohydrate and ketogenic diets show clinical potential for reducing depressive and anxiety symptoms as adjunctive therapies for treatment-resistant mental health conditions.