Brain and Body Energy Metabolism and Potential for Treatment of Psychiatric Disorders

New Results: First RCT for Schizophrenia & Bipolar Disorder. Learn more.

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We envision a future in which the metabolic health of every individual is assessed and addressed with evidence-based interventions, leading to improved mental and physical health for all.”
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Reviews

Brain and Body Energy Metabolism and Potential for Treatment of Psychiatric Disorders

A review that highlights how brain function relies heavily on energy metabolism and that disruptions in this process are common in neuropsychiatric disorders.

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Reviews

A Retrospective Evaluation of an Online Group Ketogenic Metabolic Therapy Intervention on Mental Health Outcomes

This retrospective study found a 12-week remote ketogenic metabolic therapy program feasible and associated with reduced depression and anxiety symptoms in adults with varying mental health conditions.

Reviews

Clinical Insights Into the Mechanistic Crossroads of Lamotrigine and Therapeutic Ketosis in Bipolar Depression Medically Supervised Ketogenic Diet as an Adjunctive Treatment for Moderate to Severe Depression: A Pilot Study

Lamotrigine treats both epilepsy and bipolar disorder via shared neurobiology. This review explores whether therapeutic ketosis may synergistically enhance mood stabilization and metabolic health.

Reviews

Metabolic Psychiatry Targeting Metabolic Dysregulation in Mental Health

A review of growing evidence connecting metabolic dysfunction to mental health outcomes across psychiatric disorders. This review ranks metabolic interventions by evidence strength and clinical recommendation.