Retrospective Case Study: Ketogenic Metabolic Therapy in the Effective Management of Treatment-Resistant Depressive Symptoms in Bipolar Disorder

New Results: First RCT for Schizophrenia & Bipolar Disorder. Learn more.

Peers & Families

Learn how metabolic health could play a powerful role in mental health recovery. Whether you're supporting a loved one or navigating your own path, this space offers practical insights and hope.
Overview
Navigate Your Care
Find Your People
For Clinicians

Reimagine treatment by exploring tools to integrate metabolic therapies into your practice and learn how to use ketogenic interventions as first-line or adjunctive options to improve outcomes in serious mental illness.
Overview
Training & Education
Science

Explore our curated database of peer-reviewed literature connecting metabolic and mental health. Browse active and published clinical trials of ketogenic therapy for psychiatric conditions, and learn from interviews with pioneering scientists.
Overview
Clinical Evidence
Active Trials
Research Database
Resources

Access curated resources to stay informed and take action, from scientific summaries to clinical evidence to videos, podcasts and more. Whether you're tracking research or exploring topics, these tools are here to help.
Overview
Topics by Diagnosis
Special Topics
Curated Picks
News
Episodes
Blog
THINK + SMART

THINK+SMART is a free, self-guided program that helps you explore ketogenic and lifestyle strategies for mental health, offering science-backed tools and lived experience to support personalized healing.
Overview
Stories & Strategies
Share Your Story
THINK + SMART FAQ
Get Started
About Us

We envision a future in which the metabolic health of every individual is assessed and addressed with evidence-based interventions, leading to improved mental and physical health for all.”
- Jan Baszucki Founder, Metabolic Mind
Our Story
Our Team
Contact
Awards
Metabolic Mind FAQ
Subscribe

Case Series

Retrospective Case Study: Ketogenic Metabolic Therapy in the Effective Management of Treatment-Resistant Depressive Symptoms in Bipolar Disorder

A case study about how ketogenic therapy improved treatment-resistant depressive symptoms in a patient with bipolar disorder, leading to a stabilized mood, enhanced quality of life, and reduced medication dependence.

Continue reading:

Case Series

Ketogenic Metabolic Therapy for Treatment-Resistant Post-Traumatic Stress Disorder (PTSD): A Retrospective Case Report

A case report found that a 45-year-old with treatment-resistant PTSD had reductions in PTSD, depression, and anxiety symptoms after 25 weeks on a ketogenic diet.

Case Series

Emergence of Hypomania and Mania Following Initiation of a Ketogenic Diet: Case Series

This case series describes nine participants experiencing mood changes after starting ketogenic therapy. Patients and doctors should be aware of risks and strategies to manage symptoms.

Case Series

Case Report: Metabolic, Inflammatory, and Neurological Improvements After a Ketogenic Diet in a Woman With Treatment-Resistant Schizophrenia and Metabolic Syndrome

This case report describes a 48-year-old woman with treatment-resistant schizophrenia and metabolic syndrome who completed a 5-week inpatient medical ketogenic diet. She showed notable reductions in insulin resistance...