The Ketogenic Diet as a Treatment for Mood Disorders

New Results: First RCT for Schizophrenia & Bipolar Disorder. Learn more.

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Reviews

The Ketogenic Diet as a Treatment for Mood Disorders

Review of evidence about how ketogenic diets may improve mood disorders by targeting metabolic dysfunctions, including mitochondrial issues, inflammation, oxidative stress, and insulin resistance, as explored in recent clinical trials, case reports, and preclinical studies.

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Reviews

Clinical Insights Into the Mechanistic Crossroads of Lamotrigine and Therapeutic Ketosis in Bipolar Depression Medically Supervised Ketogenic Diet as an Adjunctive Treatment for Moderate to Severe Depression: A Pilot Study

Lamotrigine treats both epilepsy and bipolar disorder via shared neurobiology. This review explores whether therapeutic ketosis may synergistically enhance mood stabilization and metabolic health.

Reviews

Metabolic Psychiatry Targeting Metabolic Dysregulation in Mental Health

A review of growing evidence connecting metabolic dysfunction to mental health outcomes across psychiatric disorders. This review ranks metabolic interventions by evidence strength and clinical recommendation.

Reviews

Metabolic Plasticity: An Evolutionary Perspective on Metabolic and Circadian Dysregulation in Bipolar Disorder

This perspective review examines bipolar disorder through a metabolic lens. It highlights how nutrition, seasonal light, and metabolic shifts may contribute to symptom instability.