Ketogenic Therapy as a Potential Novel Treatment Approach for PTSD: An Integrative Review and Proposed Mechanistic Model

New Results: First RCT for Schizophrenia & Bipolar Disorder. Learn more.

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Reviews

Ketogenic Therapy as a Potential Novel Treatment Approach for PTSD: An Integrative Review and Proposed Mechanistic Model

This integrative review of 16 studies suggests ketogenic therapies targeting brain metabolic pathways may improve PTSD, though robust human clinical trials remain lacking.

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Reviews

Metabolic Plasticity: An Evolutionary Perspective on Metabolic and Circadian Dysregulation in Bipolar Disorder

This perspective review examines bipolar disorder through a metabolic lens. It highlights how nutrition, seasonal light, and metabolic shifts may contribute to symptom instability.

Reviews

Clinical Insights Into the Mechanistic Crossroads of Lamotrigine and Therapeutic Ketosis in Bipolar Depression Medically Supervised Ketogenic Diet as an Adjunctive Treatment for Moderate to Severe Depression: A Pilot Study

Lamotrigine treats both epilepsy and bipolar disorder via shared neurobiology. This review explores whether therapeutic ketosis may synergistically enhance mood stabilization and metabolic health.

Reviews

The Ketogenic Diet for Depression and Anxiety: Implications for Practice

This review suggests low-carbohydrate and ketogenic diets show clinical potential for reducing depressive and anxiety symptoms as adjunctive therapies for treatment-resistant mental health conditions.