Modeling Combined Schizophrenia-Related Behavioral and Metabolic Phenotypes in Rodents

Fecal transplants from ketogenic diet-fed mice into a validated schizophrenia mouse model improved behavioral deficits. This suggests gut microbiome changes may help drive the ketogenic diet’s beneficial effects.

This pre-clinical study found that combining a ketogenic diet with regular voluntary exercise significantly reduced anxiety and depression-like behaviors in an animal model.

This pre-clinical study found that fasting or a short-term ketogenic diet can prevent rapid increases in blood glucose typically seen with antipsychotic medications.